eng Enviro Research Publishers Current Agriculture Research Journal 2347-4688 2321-9971 2024-04-20 12 1 146 160 18859 article Solomon Teshome 1 Arega Amide 2 Miresa Mitiku 2 Oromia Agricultural Research Institute, Crop Research Process, Finfine Bore Agricultural Research ceneter, Crop research Process, Bore Sweet potato is a crucial crop for food security and income generation. Sweet potato vine length, number of stems, average number of roots per plant, average root weight, marketable root yield, non-marketable root yield, and total sweet potato root yield were determined by the NPSB and nitrogen fertilizer application rates (p<0.01). Using the right fertilizer recommendations can improve crop growth and yield while minimizing resource use. Both NPSB and Nitrogen fertilizer rates had a highly significant impact on root number, root weight, marketable root yield, unmarketable root yield, and total root yield. The combination of 100 kg ha^-1 NPSB fertilizer and 69 kg ha^-1 of Nitrogen fertilizer gave the highest marketable root yield (553.09 qt ha^-1). The treatment with 100 kg ha^-1 NPSB fertilizer and 46 kg ha^-1 Nitrogen fertilizer demonstrated the best result in terms of marginal rate of returns, with a marginal revenue of 17872%. To optimize sweet potato productivity in the Adola rede region, it is recommended to apply 100 kg ha^-1 NPSB and 46 kg ha^-1 nitrogen fertilizer. In general, cultivation in the Adola rede region can be optimized by applying a combination of 100 kg ha^-1 of NPSB fertilizer and 46 kg ha^-1 of nitrogen, resulting in improved plant growth and marketability, higher root yields and cost efficiency. https://www.agriculturejournal.org/volume12number1/determining-the-profitability-of-different-npsb-and-nitrogen-fertilizer-rates-on-yield-and-yield-attributes-of-sweetpotato-ipomoea-batatas-l-in-the-midland-areas-of-guji-southern-oromia-ethiopia/ Adola rede; Crop yield; Fertilizer recommendations; Productivity; Sweet potato